WebMar 30, 2024 · Here's some chemistry and some history. First, we will examine a decongestant that actually works: pseudoephedrine. It's a natural product from plants of the Ephedra genus, especially E. sinica, where it occurs along with ephedrine and other alkaloids. The (S,S) and (R,R) enantiomers are known as pseudoephedrine, while the (S,R) … WebFor long-acting oral dosage form (extended-release capsules or extended-release tablets): Adults and children 12 years of age and older—120 mg every 12 hours, or 240 mg every …
Pseudoephedrine Uses, Dosage & Side Effects - Drugs.com
WebJan 25, 2024 · Pseudoephedrine is used to treat nasal and sinus congestion, or congestion of the tubes that drain fluid from your inner ears, called the eustachian tubes. Pseudoephedrine may also be used for... Pseudoephedrine was withdrawn from sale in 1989 due to concerns about adverse cardiac side effects. New Zealand. In New Zealand, pseudoephedrine is currently classified as a Class B Part II controlled drug in the Misuse of Drugs Act 1975, making it illegal to supply or possess except on prescription. See more Pseudoephedrine (PSE) is a sympathomimetic drug of the phenethylamine and amphetamine chemical classes. It may be used as a nasal/sinus decongestant, as a stimulant, or as a wakefulness-promoting agent See more Common adverse drug reactions (ADRs) associated with pseudoephedrine therapy include central nervous system stimulation, insomnia, … See more Concomitant or recent (previous fourteen days) monoamine oxidase inhibitor use can lead to hypertensive reactions, including hypertensive crises. The … See more There have been reports of off-label uses of pseudoephedrine for its stimulant properties. Long-distance truck drivers and athletes, for … See more Pseudoephedrine is a stimulant, but it is well known for shrinking swollen nasal mucous membranes, so it is often used as a decongestant. It reduces tissue hyperemia, edema, and nasal congestion commonly associated with colds or allergies. … See more Pseudoephedrine is a sympathomimetic amine. Its principal mechanism of action relies on its direct action on the adrenergic receptor system. … See more Pseudoephedrine is a diastereomer of ephedrine and is readily reduced into methamphetamine or oxidized into methcathinone. Nomenclatures The dextrorotary (+)- or d- enantiomer is (1S,2S) … See more teameffujoe
Pseudoephedrine (Oral Route) - Mayo Clinic
WebIn 1996, the company began testing a patented decongestant ingredient known as "minus" pseudoephedrine. The company claimed animal tests showed this altered version offered sinus relief comparable to the current "plus" pseudoephedrine. The difference was that it couldn't be converted to methamphetamine, an illegal drug used recreationally. WebFeb 20, 2024 · Pseudoephedrine was first known as a natural substance that occurs in shrubs of the Ephedra genus, which grow worldwide. Almost all commercial … WebPseudoephedrine has been widely used as a chiral auxiliary for carboxylic acid derivatives (see Chapters 4.11 and 4.17).This auxiliary has been applied to many types of reactions, such as α-alkylation, Mannich reaction, conjugate addition, and oxidation, 44c though the mechanism of the chirality induction, including whether chelation is involved or not, is still … southwest ticketing office in phoenix az